The premodiALS project is set out for 36 months and is divided into 7 work packages:

WP 1: Recruitment of a PGMC Cohort (Paul Lingor, Markus Weber, Philippe Corcia, Yossef Lerner, and Michael Benatar as an external partner).

WP 2: Development of a Questionnaire Based on EARLY-ALS Study Results (Paul Lingor and Michael Menden).

WP 3: Characterization of PGMC Molecular Landscape (Paul Lingor, Nicholas Ashton, Wojciech Kuban, as well as Christof Lenz and Mary-Louise Rogers as external partners).

WP 4: Bioinformatic Data Integration, Fingerprint Generation and Validation (Michael Menden).

WP 5: Recruitment of Independent Validation Cohort and Validation of PGMC Fingerprint (all).

WP 6: Supportive Recruitment into Discovery and Validation Cohorts (Hilmi Uysal and Norbert Zilka).

WP 7: Metabolomic Analyses (Norbert Zilka).